IT'S EMBARRASSING, IT'S PAINFUL AND ALMOST A MILLION PEOPLE SUFFER IN SILENCE, SOME TOO SHY TO EVEN TELL THEIR DOCTORS.
NOW A NEW TREATMENT IS CHANGING PEOPLE'S LIVES WHO HAVE ULCERATIVE COLITIS.
LESLIE SCHWARTZ HOPES WHAT'S INSIDE THIS BAG WILL ALLOW HIM TO ENJOY LIFE AGAIN.
"We've tried just about everything else there is to try."
LESLIE HAS ULCERATIVE COLITIS.
THAT'S WHEN ULCERS AND INFLAMMATION FORM ON THE LINING OF THE COLON AND INTESTINE. HE'S LIVED WITH THE UNCOMFORTABLE SYMPTOMS AND 10 TO 15 TRIPS TO THE BATHROOM A DAY FOR ALMOST 10 YEARS.
"Very inconvenient because I was bleeding a lot, going to the bathroom a lot."
"It's hard to tell your friends what's wrong, and you just kind of have to withdraw from life."
DOCTOR WILLIAM SANDBORN SAYS PATIENTS LIKE LESLIE CAN HAVE SURGERY, BUT THAT MEANS REMOVING THE COLON AND NEEDING AN ILEOSTOMY BAG. INSTEAD, HE OFFERED LESLIE AN EXPERIMENTAL THERAPY.
"What we think is happening with this medication is it's promoting healing of that inflamed lining of the bowel."
M-D-X-1100 WORKS BY BLOCKING A PROTEIN CALLED CHEMOKINE, CLEARING IT FROM THE BODY, SO INFLAMMATION CAN'T OCCUR.
CURRENT DRUGS CAN HINDER THE IMMUNE SYSTEM, LEAD TO INFECTION AND EVEN INCREASE THE RISK OF CANCER. M-D-X-1100 PROMOTES HEALING.
"It seems to be really targeting the colon, so it leaves most of the rest of the body alone and aims to the colon."
BUT IF THEY STOP THE THERAPY, SYMPTOMS WILL COME BACK. TODAY IS LESLIE'S FIRST TREATMENT, AND HE HAS HIGH HOPES.
"I want to go back and play golf, too actually. You know, there's only one restroom between the first and the ninth tee."
A MAN WHO'S READY TO GET BACK TO AN ACTIVE LIFE WITHOUT AN EMBARRASSING PROBLEM HOLDING HIM BACK.
PATIENTS GET AN INFUSION OF THE DRUG ABOUT EVERY FOUR WEEKS.
SO FAR, IT'S SHOWN GOOD RESULTS IN A PHASE ONE STUDY.
IT'S NOW IN PHASE TWO OF TESTING.
ONE INTERESTING FACT: SMOKING ACTUALLY PROTECTS PATIENTS FROM ULCERATIVE COLITIS.
SMOKERS HAVE ABOUT HALF THE RISK OF DEVELOPING THE DISEASE COMPARED TO NONSMOKERS.
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