It happened around 10:30 on I-44 in Cotton County near Walters.
Troopers say the victim who's identified as Larry Samford was traveling with two friends who were on separate motorcycles.
They say Samford was changing lanes when his motorcycle hit one of his friends' cycle.
He was throw from his motorcycle into the roadway and troopers say the third motorcycle hit him.
Samford was pronounced dead at the hospital.
The two other drivers, troopers say, were not injured.
Copyright 2015 Nexstar Broadcasting, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.