It happened a little after 4.p.m. Friday afternoon on Brosch Road about a half a mile west of Highway 25.
DPS Trooper Tony Fulton said the woman was heading westbound on Brosch when her Chevrolet hit the tow truck on the south side of the road head one.
The female driver was taken to Electra Memorial Hospital where she was pronounced dead.
According to DPS officials, her passenger left the scene with unknown injuries.
The 58-year-old driver of the pickup was not injured.
DPS is still investigating the cause of the crash.
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