The stabbing happened at about 7:00 am at a surgical unit of Good Shepherd Medical Center in Longview, about 120 miles east of Dallas.
The suspect fled the scene but was located by police nearby and detained.
The suspect, 22-year-old Kyron Yempleton, was arraigned Tuesday afternoon on charges of murder and four counts of aggravated assault with a deadly weapon.
Police have not released a possible motive for the stabbings.
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