After 22 years, he's preparing to hand the show off to "SNL" alum and "Late Night" host Jimmy Fallon.
Fallon says he is thrilled to have the opportunity to host one of the longest running late night talk shows, and hopes, that like Leno, he's hosting the show for 20+ years.
"I would hope, I would love it absolutely. It'd be the greatest. I was talking to Seinfeld about this and he says, you sure you want this? It's the Pope job. This is the Pope job!! You're gonna do this, you want this, the rest of your life, you're gonna do this job. It's up to you!" joke Fallon.
As for Leno, he says he's anxious to get back on stage and do a comedy routine.
"I really like being a standup comedian. It'll be fun to go back and do that a lot more," Leno said.
Following a week of Winter Olympics, Fallon will star in his new role beginning Monday, February 17th on NBC.
Copyright 2015 Nexstar Broadcasting, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.