Malaysia Airlines says it has lost contact with a plane with 239 aboard travelling from Kuala Lumpur to Beijing.
Mother who drove van with three children inside into ocean charged with attempted murder.
Fallout continues over changes in the ways consumers can earn and redeem air miles.
Daylight Saving Time begins Saturday night, which to many is a welcome sign of the end of a miserable winter.
Letter mailed eight years ago finally arrives at its destination, just a few miles from where it was sent.
President Obama calls for international monitors in Ukraine, says Russia's actions violate international law.
Chris Christie, Ted Cruz and other prominent GOP leaders among the speakers at Conservative Political Action Conference underway in Washington.
Study finds e-cigarettes are increasingly popular with teens, many of whom use them with tobacco cigarettes as well.
The House has approved a $1 billion loan guarantee package for Ukraine, as part of the U.S. effort to support the new government as Russia continues to occupy the Crimean Peninsula.
Texas college hands out coasters that test whether your drink has been drugged.
Massachusetts high court rules that the practice of upskirting does not violate any state laws.
She has gone from being one of the slower runners on her high school team to one of the fastest distance runners in the nation, a rise fueled by an improbable motivation.
Top Republicans say they'll support economic sanctions against Russia as punishment for aggression in Ukraine.
California's drought could cause major problems for North America's second largest sake producer.
Good Samaritans rush to pull children from minivan after mother drives into the ocean off Daytona Beach, Florida.
More churches are taking Ash Wednesday out of the sanctuary and onto the streets.
The College Board is making far-reaching changes to the SAT exam that it says will help close the test's socioeconomic gap among college aspirants.
A senior executive at Target has resigned following the massive credit card data breach at the retail giant.
President Obama and Secretary of State John Kerry push back on Russia's actions in Ukraine.
President Obama releases proposed 2015 budget.
Confused about why we change our clocks and learn some of the unusual time zone issues around the U.S. & the world.
The Russian military has given Ukrainian forces in Crimea until 5 a.m. Tuesday (10 p.m. ET Monday) to surrender or face a "storm," Interfax news agency reported.
A Mississippi man who was thought to be dead and was taken to morgue in body bag turns out not to be dead at all.
Russia appears to be ignoring the U.S. and its allies request to stay out of the Ukraine.
New survey finds American children aren't getting enough sleep, and electronic devices are to blame.
As your local election headquarters, we continue to take a look at the contested races in Tuesday's primary election. Tonight we're introducing you to the three candidates who want the Republican nod for the 13th District Congressional seat.
Mark Barger previews Sunday's Academy Awards ceremony.
Large numbers of Russian troops were reported landing at a military air base in Crimea Friday, prompting Ukraine to accuse Russia of a military invasion.
A federal judge on Thursday ordered the state of Kentucky to recognize same-sex marriages performed in other states.
The FDA is proposing the first changes to those little black-and-white food labels in more than 20 years, and they aim to take a more realistic look at what people eat.
Attorney General Eric Holder was taken to a Washington hospital Thursday after experiencing shortness of breath, Justice Department officials said.
General Motors is expanding its recall of certain older model vehicles to correct a problem with the ignition switches, which could fail and shut-off the engine.
Obesity rates are falling among America’s pudgy preschoolers, perhaps the latest sign that the super-sized nation is getting a handle on its weight problem, according to new figures from government health officials.
Four-year-old unlocks cell phone and calls 911 after dad is severely injured while cutting wood.
Study links autism, ADHD and other disorders to children born to fathers 45 and older.
President Obama threatens to pull all U.S. forces from Afghanistan is new security agreement isn't signed.
Arizona Governor Jan Brewer holds final decision on new state law that would allow discrimination based on sexual orientation.
Mystery illness has left some children with permanently paralyzed limbs. Doctors are not sure what is causing the illnesses, but suspect a virus.
Blind Missouri man shows off his ability to make three point shots.
First lady Michelle Obama stepped up the pressure Tuesday against companies selling junk food to students, announcing a new government proposal that would ban advertising of sodas and unhealthy snacks in public schools.
Dozens of people line up and pay to see what one Texas hunter claims is the body of Bigfoot.
Ohio bus driver is alive thanks to what some might call divine intervention. He was shot twice in the chest but a pocket-sized devotional book stopped the bullets.
Oklahoma student brings to life music notes hidden in a 500-year-old painting.
Critics and fans alike are calling Monday night's premiere of 'Late Night with Seth Meyers' a big success.
Singers and coaches compete when "The Voice" returns to NBC Monday night.
The nations governors meet with President Obama as part of their winter conference.
Comedy legend Harold Ramis, best known for his classic role in the “Ghostbusters” films, has died, his wife told the Chicago Tribune. He was 69.
Former Wells Fargo manager sues bank after she's fired for bringing a handgun onto company property.
Oregon family says gas station wouldn't allow them to use fire extinguishers after their vehicle caught on fire.
Monday night Seth Meyers takes over as host of NBC's "Late Night".
Secretary of Defense outlines massive budget cuts aimed at shrinking the U.S. military.
A radiation leak at a nuclear waste storage site below the New Mexico desert has been plugged, but the facility will remain closed for at least the next three weeks, officials said late Thursday.
President Viktor Yanukovych signed a deal with Ukraine's main opposition leaders on Friday brokered to end the deadly violence that put the country on the brink of civil war.
More bloodshed occurred in Ukraine Tuesday despite a truce called by the government and opposition.
Who knew that NBC Nightly News Anchor Brian Williams could rap?
Michigan families work together to build massive backyard luge.
President Obama says Ukrainian government will be held responsible for deadly clashes as he arrives for summit in Mexico.
There is a nationwide shortage of clowns. Gran Boxleitner goes to the clown capital of the U.S.
There's a growing push to expand absentee voter rights ahead of the upcoming midterm elections.
Ranchers are using ultrasound to help get better steaks from their cattle.