Many obese men and women are turning to surgery to help them lose the extra weight. But for women who are planning a pregnancy, is it a good idea?
A new study suggests that for obese women who choose weight-loss surgery to bring their weight under control, having the procedure may also benefit their future children.
A Canadian study found that children born after their mother had lost considerable weight from gastric bypass surgery were slimmer than their pre-surgery siblings and had fewer risk factors for diabetes or heart disease later in life.
The findings showed that numerous genes linked to obesity-related health problems worked differently in the younger siblings than in their older brothers and sisters.
The researchers looked at the genes of 50 children who were born to 20 mothers before or after they had gastric bypass surgery. The children were on average about 15 years old.
The moms were between the ages of 35 to 51 and were all classified as obese before they had the procedures. They all lost almost 100 pounds after the surgery.
The type of gastric bypass surgery performed on the mothers who participated in the study is called a biliopancreatic diversion with duodenal switch procedure. It is not used as often as the more common Roux-en-Y gastric bypass procedure. In the biliopancreatic diversion with duodenal switch procedure, a larger part of the stomach is left intact while bypassing most of the intestine.
In the children born after their mothers surgery and weight loss, researchers found 5,698 genes were expressed differently than their older siblings. What that means is that the mothers didnt pass on different genes to their children, but how those genes operated in the childrens bodies were different in the pre and post surgery children. The reason may be that factors inside the womb seem to affect the dimmer switches that develop on a fetus' genes " chemical changes that make genes sp